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Depression and Parkinson’s Disease: Current Knowledge

2013; Springer Science+Business Media; Volume: 13; Issue: 12 Linguagem: Inglês

10.1007/s11910-013-0409-5

1534-6293

Laura Marsh,

Restless Legs Syndrome Research

Depressive disturbances are common in patients with Parkinson’s disease (PD) and influence many other clinical aspects of the disease. In addition to causing inherent emotional distress, depressive disorders negatively impact quality of life, motor and cognitive deficits, functional disability, and other psychiatric comorbidities in patients with PD. Knowledge of the pathophysiology of PD depression remains limited. However, clinical studies demonstrate the efficacy of medications and psychotherapies for PD depression, underscoring the importance of their timely detection and concerted management.