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ANTIBODIES TO FOUR GRAM-NEGATIVE BACTERIA IN RHEUMATOID ARTHRITIS WHICH SHARE SEQUENCES WITH THE RHEUMATOID ARTHRITIS SUSCEPTIBILITY MOTIF

1996; Oxford University Press; Volume: 35; Issue: 6 Linguagem: Inglês

10.1093/rheumatology/35.6.592

1462-0332

Harmale Tiwana, CR Wilson, Philip Cunningham, Allan Binder, Alan Ebringer,

Spondyloarthritis Studies and Treatments

The bacteria Proteus, Serratia, Escherichia and Pseudomonas possess sequences resembling the rheumatoid arthritis susceptibility sequence EQRRAA, but antibodies were elevated only to Proteus in 66 RA patients (P<0.001) when compared to 61 active ankylosing spondylitis patients and 60 controls.