Artigo Acesso aberto Revisado por pares

CAVER Analyst 1.0: graphic tool for interactive visualization and analysis of tunnels and channels in protein structures

2014; Oxford University Press; Volume: 30; Issue: 18 Linguagem: Inglês

10.1093/bioinformatics/btu364

ISSN

1367-4811

Autores

Barbora Kozlíková, Eva Šebestová, Vilém Šustr, Jan Brezovský, Ondřej Strnad, Lukáš Daniel, David Bednář, Antonín Pavelka, Martin Maňák, Martin Bezděka, Petr Beneš, Matúš Kotry, Artur Góra, Jir̆ı́ Damborský, Jiří­ Sochor,

Tópico(s)

Mass Spectrometry Techniques and Applications

Resumo

Abstract Summary: The transport of ligands, ions or solvent molecules into proteins with buried binding sites or through the membrane is enabled by protein tunnels and channels. CAVER Analyst is a software tool for calculation, analysis and real-time visualization of access tunnels and channels in static and dynamic protein structures. It provides an intuitive graphic user interface for setting up the calculation and interactive exploration of identified tunnels/channels and their characteristics. Availability and Implementation: CAVER Analyst is a multi-platform software written in JAVA. Binaries and documentation are freely available for non-commercial use at http://www.caver.cz . Contact: jiri@chemi.muni.cz or sochor@fi.muni.cz Supplementary information: Supplementary data are available at Bioinformatics online.

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