BRAF Inhibitors Induce Metastasis in RAS Mutant or Inhibitor-Resistant Melanoma Cells by Reactivating MEK and ERK Signaling
2014; American Association for the Advancement of Science; Volume: 7; Issue: 318 Linguagem: Inglês
10.1126/scisignal.2004815
ISSN1937-9145
AutoresBerta Sánchez-Laorden, Amaya Virós, María Romina Girotti, Malin Pedersen, Grazia Saturno, Alfonso Zambon, Dan Niculescu‐Duvaz, Samra Turajlic, Andrew Hayes, Martin Gore, James Larkin, Paul Lorigan, Martin Cook, Caroline J. Springer, Richard Marais,
Tópico(s)Synthesis and biological activity
ResumoWhen therapy leads to cancer metastasis, knowing where else to target in the pathway may be the key to successful treatment.
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