Magnetic Tagging of Therapeutic Cells for MRI
2009; Society of Nuclear Medicine and Molecular Imaging; Volume: 50; Issue: 2 Linguagem: Inglês
10.2967/jnumed.108.053546
ISSN1535-5667
AutoresMatthew D. Budde, Joseph A. Frank,
Tópico(s)Pluripotent Stem Cells Research
ResumoTransplantation of stem cells or immune cells has shown promise for the treatment of several diseases. Monitoring magnetically labeled cells with MRI has furthered our understanding of cellular migration and the pathophysiology of diseases in experimental models. These studies should pave the way for guiding clinical trials using cell-based therapies. This review briefly describes the various methods used to label and track cells with MRI and the potential for such methods to translate to human applications.
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