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The Human UDP-Glucuronosyltransferases: Structural Aspects and Drug Glucuronidation

2003; Taylor & Francis; Volume: 35; Issue: 4 Linguagem: Inglês

10.1081/dmr-120026397

1097-9883

Mohamed Ouzzine, Lydia Barré, Patrick Netter, Jacques Magdalou, Sylvie Fournel‐Gigleux,

Biochemical and Molecular Research

UDP-glucuronosyltransferases (EC 2.4.1.17) constitute a large multigenic family of enzymes that are involved in phase II of drug metabolism (Mackenzie et al., [1997]). These endoplasmic reticulum (...