Artigo Acesso aberto Produção Nacional Revisado por pares

Molecular and chromosomal mutations among children with B-lineage lymphoblastic leukemia in Brazil’s Federal District

2009; Research Foundation of Ribeirão Preto; Volume: 8; Issue: 1 Linguagem: Inglês

10.4238/vol8-1gmr582

ISSN

1676-5680

Autores

Débora Rabello Mesquita, José Carlos Córdoba, Isis Quezado Magalhães, Mara S. Córdoba, J.R.C. Oliveira, Ana Katherine Gonçalves, Íris Ferrari, C. Martins-de-Sá,

Tópico(s)

Childhood Cancer Survivors' Quality of Life

Resumo

Acute lymphoblastic leukemia (ALL) accounts for approximately 80% of all acute leukemias during childhood.Chromosomal anomalies resulting from gene fusion, which are frequent in leukemias, create hybrid transcripts, the great majority of which encode transcription factors.We analyzed 88 pediatric patients (median age 7.3 years) who had B-lineage acute lymphoblastic leukemia (B-ALL), using reverse tran-©FUNPEC-RP www.funpecrp.com.

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