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Characterization of iturin a in antibiotics from various strains of Bacillus subtilis.

1976; Springer Nature; Volume: 29; Issue: 10 Linguagem: Inglês

10.7164/antibiotics.29.1043

1881-1469

Françoise Besson, F. Peypoux, Georges Michel, L. Delcambe,

Biopolymer Synthesis and Applications

Iturin A, an antifungal lipopeptide characterized by the presence of homologous liposoluble beta-aminoacids was found to be the active component to bacillomycin B, bacillomycin R and eumycin. Iturin A was identified by thin-layer chromatography, aminoacid analysis and by characterization of liposoluble aminoacids and peptides. Another two preparations: the antibiotic of Raubitschek and the bacillomycin of Landy et al. contain components of the same structural type but they are different from iturin A.