Blastocyst expansion, inner cell mass (ICM) formation, and trophectoderm (TM) quality: is one more important for implantation?
2001; Elsevier BV; Volume: 76; Issue: 3 Linguagem: Inglês
10.1016/s0015-0282(01)02038-6
ISSN1556-5653
AutoresNikica Zaninović, Rosemary Berrios, Robert N. Clarke, Richard Bodine, Z. Ye, Lucinda L. Veeck,
Tópico(s)Reproductive Biology and Fertility
ResumoObjective: The use of blastocyst culture for in vitro fertilization has been associated with an increase in implantation rates. Better synchronization between preembryo and endometrium and selection of conceptuses with a high implantation potential can be attributed to the success. To correlate morphology with implantation capability, a blastocyst grading system was developed. The system is based on overall expansion, and ICM and TM morphology. Correlation has been demonstrated between this grading system and subsequent implantation rates. However, no report has been published correlating blastocyst expansion, ICM, or TM quality as separate and individual parameters. It may be important to recall that the ICM will form the embryo, while TM, important for implantation, will give rise to the placenta.
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