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Artigo Acesso aberto Produção Nacional Revisado por pares
BIBTEX RIS

Seroprevalence of human parvovirus B19 in a suburban population in São Paulo, Brazil

2008; UNIVERSIDADE DE SÃO PAULO; Volume: 42; Issue: 3 Linguagem: Inglês

10.1590/s0034-89102008005000019

ISSN

1518-8787

Autores

E M M Huatuco, Edison Luíz Durigon, Fabiana L. A. S. Lebrun, Saulo Duarte Passos, Rosa Estela Gazeta, Raymundo Soares Azevedo, Eduardo Massad,

Tópico(s)

Blood groups and transfusion

Resumo

To analyze the prevalence of IgG antibodies to human parvovirus B19.Cross-sectional study in a suburban community in São Paulo, Southeastern Brazil, between November 1990 and January 1991. Randomly selected (N=435) representative samples of sera were collected from healthy children older than 15 days old and adults up to 40 years old. IgG antibodies were detected using ELISA.High prevalence of IgG antibodies to B19 parvovirus was found in 87% of newborns. The prevalence of maternally derived IgG antibodies exponentially plunged up to the 19th month of age. Low prevalence of antibodies was found in the first 4 years of life, increasing up to 72% in those aged 31-40 years. It was estimated that the average age of first infection in this population is 21 +/- 7 years old and the optimal age for vaccination with a hypothetical vaccine would be 1 year of age.Parvovirus B19 IgG antibody prevalence was high in newborns and those aged 31-40 years. The analysis by age groups showed a pattern similar to that found in previous studies, i.e., low prevalence of infection in children that increases with age.

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