Impact of the intensity of microemboli on neurocognitive outcome following cardiopulmonary bypass
2013; SAGE Publishing; Volume: 28; Issue: 3 Linguagem: Inglês
10.1177/0267659112470693
ISSN1477-111X
AutoresSuat Doğancı, Serdar Günaydın, Orhan Murat Koçak, Sevda Yılmaz, Ufuk Demirkılıç,
Tópico(s)Hemodynamic Monitoring and Therapy
ResumoThis study aimed to determine whether there was any association between the intensity of intraoperative gaseous microembolic signals (GME), neuropsychological testing and clinical outcome in high-risk patients undergoing coronary artery surgery (CABG).Over a 6-month period, GME activity was monitored in 102 Euroscore 6+ patients during cardiopulmonary bypass (CPB) with a conventional 32-micron arterial filter by non-invasive, real-time ultrasonic device. Cognitive tests; line bisection, the Stroop test, finger tapping, and the Rey Auditory Verbal Learning Test were performed at baseline, postoperative one week and postoperative one month.The distribution of GME activity showed that there were three groups of patients: >500 total emboli (n = 38); 250 to 500 emboli (n = 30) and 500 emboli patients versus control (<250 emboli) in postoperative week one, but resolved in one month.Correlation between intraoperative GME intensity and neurocognitive tests suggests that the level of GME might have a role in determining the psychological outcome after CABG with CPB.
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