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Evaluation of “Gastromiro” for bowel opacification during computed tomography: comparison with diatrizoate and barium sulphate

1993; Wiley; Volume: 66; Issue: 788 Linguagem: Inglês

10.1259/0007-1285-66-788-681

1748-880X

G.J. Doyle, Steve O’Donnell, John R. McDonald, L.N.S. Murthy, M.J. Keir, Andrew Wright,

Anorectal Disease Treatments and Outcomes

Abstract A new oral formulation of iopamidol, “Gastromiro”, was evaluated as a bowel contrast agent during abdominal computed tomography (CT). Comparison was made with the well established agents sodium/ meglumine diatrizoate (“Urografin 370”) and dilute barium sulphate (“E-Z CAT”) in a randomized, blind study of 150 consecutive patients undergoing abdominal and/or pelvic CT. Parameters assessed included quality of bowel opacification, artefact generation, contrast-medium palatibility, side effects and cost. No significant difference was found between the three contrast media in stomach- or small-bowel opacification. E-Z CAT was superior at opacifying the caecum/ascending colon. No compelling reason to choose a particular agent was found in the other assessed parameters, but cost is a significant factor.