Artigo Revisado por pares

The Effect of MAPT H1 and APOE ε4 on Transition from Mild Cognitive Impairment to Dementia

2011; IOS Press; Volume: 22; Issue: 4 Linguagem: Inglês

10.3233/jad-2010-101011

ISSN

1875-8908

Autores

Lluı́s Samaranch, Sebastián Cervantes, Ana Barabash, Álvaro Alonso, José A. Cabranes, Isabel Lamet, Inés Ancín, Elena Lorenzo, Pablo Martínez‐Lage, Alberto Marcos, Jordi Clarimón, Daniel Alcolea, Alberto Lleó, Rafael Blesa, Teresa Gómez‐Isla, Pau Pástor,

Tópico(s)

Neurological Disease Mechanisms and Treatments

Resumo

Microtubule-associated protein tau (MAPT) and apolipoprotein E (APOE) are involved in the pathogenic mechanisms of Alzheimer's disease (AD). We prospectively followed three longitudinal independent samples (total n = 319) with amnestic mild cognitive

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