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Visceral Leishmaniasis in Renal Transplant Recipients: Successful Treatment with Liposomal Amphotericin B (AmBisome)

1999; Oxford University Press; Volume: 28; Issue: 6 Linguagem: Inglês

10.1086/514784

1537-6591

John Boletis, Angelos Pefanis, Charalampos Stathakis, Helen Helioti, Apostolos Kostakis, Helen Giamarellou,

Hepatitis Viruses Studies and Epidemiology

Visceral leishmaniasis (VL) is a rare disease in renal transplant recipients. Liposomal amphotericin B (AmBisome) is known to be effective against VL. However, previously there has been no experience with administration of such treatment to renal transplant recipients. We report herein four patients with VL complicating renal transplantation who were treated successfully with liposomal amphotericin B (total dose, 23–40 mg/kg). Neither adverse reactions nor clinical relapses of VL were observed.