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Pandemic Influenza Vaccine Policy — Considering the Early Evidence

2009; Massachusetts Medical Society; Volume: 361; Issue: 25 Linguagem: Inglês

10.1056/nejme0908224

1533-4406

Kathleen M. Neuzil,

Viral Infections and Outbreaks Research

Policy decisions regarding influenza rest on judgments about the behavior of the virus, the impact of the disease and our ability to interdict its course.But the virus is capricious, the disease elusive, and our remedies imperfect," said a report on the 1976 swine-flu epidemic at Fort Dix. 1Two peer-reviewed articles now publicly available at NEJM.org, by Greenberg et al. (ClinicalTrials.gov number, NCT00938639) 2 and Clark et al. (NCT00943358), 3 describe preliminary data on the immunogenicity of the influenza A (H1N1) 2009 monovalent vaccine.These data have been eagerly anticipated, as governments, public health officials, and other stakeholders respond to the first influenza pandemic in over 40 years.The authors and their collaborators are to be commended for their prompt execution of the trials and rapid sharing of the results.