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Dermatitis herpetiformis and established coeliac disease

1993; Oxford University Press; Volume: 129; Issue: 6 Linguagem: Inglês

10.1111/j.1365-2133.1993.tb03333.x

1365-2133

David J. Gawkrodger, J.P. VESTEY, Siobhain M. O’Mahony, Janet Marks,

Lymphatic Disorders and Treatments

Fifteen (5.3%) of 282 patients with dermatitis herpetiformis (DH) were diagnosed as suffering from coeliac disease before the onset of their DH. This group showed a female preponderance, and a later than usual onset of DH. The mean age at which DH developed was 40.0 years, and there was a mean interval of 13.2 years between the two diagnoses. Seven patients had stopped their gluten-free diet, and a further four were poor compliers. Persistent gluten ingestion in coeliacs with a specific genetic predisposition may result in the development of DH.