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Untranslated regions of mRNAs.

2002; Springer Science+Business Media; Volume: 3; Issue: 3 Linguagem: Inglês

10.1186/gb-2002-3-3-reviews0004

1465-6914

Flavio Mignone, Carmela Gissi, Sabino Liuni, Graziano Pesole,

RNA Research and Splicing

Gene expression is finely regulated at the post-transcriptional level. Features of the untranslated regions of mRNAs that control their translation, degradation and localization include stem-loop structures, upstream initiation codons and open reading frames, internal ribosome entry sites and various cis-acting elements that are bound by RNA-binding proteins.