Artigo Acesso aberto Revisado por pares

Chromosomal Microarray versus Karyotyping for Prenatal Diagnosis

2012; Massachusetts Medical Society; Volume: 367; Issue: 23 Linguagem: Inglês

10.1056/nejmoa1203382

ISSN

1533-4406

Autores

Ronald J. Wapner, Alastair J. Martin, Brynn Levy, Blake C. Ballif, Christine M. Eng, Julia Zachary, Melissa Savage, Lawrence D. Platt, Daniel H. Saltzman, William A. Grobman, Susan Klugman, Thomas Scholl, Joe Leigh Simpson, Kimberly McCall, Vimla S. Aggarwal, Brian Bunke, Odelia Nahum, Ankita Patel, Allen N. Lamb, Elizabeth Thom, Arthur L. Beaudet, David H. Ledbetter, Lisa G. Shaffer, Laird Jackson,

Tópico(s)

Tumors and Oncological Cases

Resumo

Chromosomal microarray analysis has emerged as a primary diagnostic tool for the evaluation of developmental delay and structural malformations in children. We aimed to evaluate the accuracy, efficacy, and incremental yield of chromosomal microarray analysis as compared with karyotyping for routine prenatal diagnosis.

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