Portal de Periódicos da CAPES

CYTOTOXIC EFFECTS OF ANTITUMOR SERUM

1957; Wiley; Volume: 69; Issue: 4 Linguagem: Inglês

10.1111/j.1749-6632.1957.tb49715.x

1749-6632

Robert W. Wissler, Martin H. Flax,

Fungal Infections and Studies

Annals of the New York Academy of SciencesVolume 69, Issue 4 p. 773-794 CYTOTOXIC EFFECTS OF ANTITUMOR SERUM Robert W. Wissler, Robert W. Wissler Department of Pathology and the Argonne Cancer Research Hospital, The University of Chicago, Chicago, Ill.Search for more papers by this authorMartin H. Flax, Martin H. Flax Department of Pathology and the Argonne Cancer Research Hospital, The University of Chicago, Chicago, Ill.Search for more papers by this author Robert W. Wissler, Robert W. Wissler Department of Pathology and the Argonne Cancer Research Hospital, The University of Chicago, Chicago, Ill.Search for more papers by this authorMartin H. Flax, Martin H. Flax Department of Pathology and the Argonne Cancer Research Hospital, The University of Chicago, Chicago, Ill.Search for more papers by this author First published: December 1957 https://doi.org/10.1111/j.1749-6632.1957.tb49715.xCitations: 17 The work reported in this paper was supported in part by an institutional grant from the American Cancer Society, Inc., New York, N. Y. AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat References 1 RICH, A. R. 1951. The Pathogenesis of Tuberculosis. 2nd ed. Thomas. Springfield, Ill . 2 ARTHUS, M. & M. BRETON. 1903. Lésions cutanées produites par les injections de sérum de cheval chez le lapin anaphylactisé par et pour ce sérum. I. Compt. rend, soc. biol. 55: 1478–1480. 3 OPIE, E. L. 1924. Inflammatory reaction of the immune animal to antigen (Arthus phenomenon) and its relation to antibodies. J. Immunol. 9: 231–245. 4 CANNON, P. R. & C. E. MARSHALL. 1941. Studies on the mechanism of the Arthus phenomenon. J. Immunol. 40: 127–146. 5 FISCHEL, E. E. & E. A. KABAT. 1947. A quantitative study of the Arthus phenomenon induced passively in the rabbit. J. Immunol. 55: 337–343. 6 RICH, A. R. & J. E. GREGORY. 1943. The experimental demonstration that periarteritis nodosa is a manifestation of hypersensitivity. Bull. Johns Hopkins Hosp. 72: 65–82. 7 HOPPS, H. C. & R. W. WISSLER. 1946. The experimental production of generalized arteritis and periarteritis. J. Lab. Clin. Med. 31: 939–957. 8 HAWN, C. V. & C. A. JANEWAY. 1947. Histological and serological sequences in experimental hypersensitivity. J. Exptl. Med. 85: 571–590. 9 WISSLER, R. W., K. SMULL & J. B. LESH. 1949. The effects of various horse serum fractions in producing cardiovascular and renal lesions in rabbits. J. Exptl. Med. 90: 577–594. 10 RICH, A. R. & R. H. FOLLIS, JR. 1940. Studies on the site of sensitivity in the Arthus phenomenon. Bull. Johns Hopkins Hosp. 66: 106–122. 11 WAKSMAN, B. H. 1955. A discussion of the paper by R. A. Cooke. The allergic response and the tuberculin reaction. Ann. N. Y. Acad. Sci. 59(3): 306–307. 12 BOYD, W. C. 1956. Fundamentals of Immunology. : 406–408. 3rd ed. Interscience. New York , N. Y. 13 VAUGHAN, W. T. & J. H. BLACK. 1954. Practice of Allergy. 3rd ed. Mosby. St. Louis, Mo . 14 KENTON, H. B. 1941. The Arthus phenomenon in the rat. J. Infectious Diseases. 69: 238–242. 15 HARTLEY, G., JR. & C. C. LUSHBAUGH. 1942. Experimental allergic focal necrosis of the liver. Am. J. Pathol. 18: 323–327. 16 SEEGAL, D., B. C. SEEGAL & E. JOST. 1932. The Arthus phenomenon, local anaphylactic inflammation in the rabbit pericardium, heart and aorta. J. Exptl. Med. 55: 155–168. 17 SHEAR, M. J. & H. B. ANDERVONT. 1936. Chemical treatment of tumors. III. Separation of hemorrhage-producing fraction of B. coli filtrate. Proc. Soc. Exptl. Biol. Med. 34: 323–325. 18 SHWARTZMAN, G. 1937. Phenomenon of Local Tissue Reactivity. Hoeber. New York , N. Y. 19 APITZ, K. 1935. A study of the generalized Shwartzman phenomenon. J. Immunol. 29: 255–266. 20 AUER, J. 1920. Local autoinoculation of the sensitized organism with foreign protein as a cause of abnormal reactions. J. Exptl. Med. 32: 427–444. 21 HOPPS, H. C. 1944. Role of allergy in delayed healing and in disruption of wounds. III. Delayed healing and disruption produced by local allergic reaction (Auer phenomenon). Arch. Surgery. 48: 450–456. 22 KIRSNER, J. B. Personal communication. 23 WOGLOM, W. H. 1929. Immunity to transplantable tumours. Cancer Rev. 4: 129–214. 24 SPENCER, R. R. 1942. Tumor immunity. J. Natl. Cancer Inst. 2: 317–332. 25 BARRETT, M. K. The nature of tumor immunity. In Origins of Resistance to Toxic Agents. : 308–333. Academic Press. New York , N. Y. 26 HAUSCHKA, T. S. 1952. Immunologic aspects of cancer: a review. Cancer Research. 12: 615–633. 27 CHASE, M. W. 1952. The allergic state. In Bacterial and Mycotic Infections of Man. : 168–227. R. J. Dubos, Ed. Lippincott. Philadelphia, Pa. 28 LAWRENCE, H. S. 1956. The delayed type of allergic inflammatory response. Am. J. Med. 20: 428–447. 29 RAFFEL, S. 1956. Bacterial hypersensitivity. J. Allergy. 27: 199–212. 30 JULIANELLE, L. A. 1930. Reactions of rabbits to intracutaneous injections of pneumococci and their products. V. The development of eye reactivity to derivatives of pneumococcus. J. Exptl. Med. 51: 625–642. 31 ARONSON, J. D. 1931. The specific cytotoxic action of tuberculin in tissue culture. J. Exptl. Med. 54: 387–397. 32 RICH, A. R. & M. R. LEWIS. 1932. The nature of allergy in tuberculosis as revealed by tissue culture studies. Bull. Johns Hopkins Hosp. 50: 115–132. 33 FAVOUR, C. B. 1947. Lytic effect of bacterial products on lymphocytes of tuberculous animals. Proc. Soc. Exptl. Biol. Med. 65: 269–272. 34 BAIL, O. 1910. Übertragung der Tuberkulinempfindlichkeit. Z. Immunitätsforsch. 4: 470–485. 35 CHASE, M. W. 1945. The cellular transfer of cutaneous hypersensitivity to tuberculin. Proc. Soc. Exptl. Biol. Med. 59: 134–135. 36 KIRCHHEIMER, W. F., A. R. HESS & R. G. SPEARS. 1951. Attempts at passive transfer of tuberculin type of sensitivity with living granulocytes. Am. Rev. Tuberc. Pulmonary Diseases. 64: 516–519. 37 COLE, L. R. & C. B. FAVOUR. 1955. Correlations between plasma protein fractions, antibody titers, and the passive transfer of delayed and immediate cutaneous reactivity to tuberculin PPD and tuberculopolysaccharides. J. Exptl. Med. 101: 391–420. 38 FREUND, J. 1956. The mode of action of immunologic adjuvants. Advances in Tuberc. Research. 7: 130–148. Karger. Basel, Switzerland; New York , N. Y. 39 KABAT, E. A., A. WOLF & A. E. BEZER. 1947. The rapid production of acute disseminated encephalomyelitis in rhesus monkeys by injection of heterologous and homologous brain tissue with adjuvants. J. Exptl. Med. 85: 117–129. 40 MORGAN, I. M. 1947. Allergic encephalomyelitis in monkeys in response to injection of normal monkey nervous tissue. J. Exptl. Med. 85: 131–140. 41 WAKSMAN, B. H. & R. D. ADAMS. 1955. Allergic neuritis: an experimental disease of rabbits induced by the injection of peripheral nervous tissue and adjuvants. J. Exptl. Med. 102: 213–236. 42 VOISIN, G., A. DELAUNAY & M. BARBER. 1951. Lésions testiculaires provoquées chez le cobaye par injection d'extraits de testicules homologues. Compt. rend. 232: 1264–1266. 43 FREUND, J., G. E. THOMPSON & M. M. LIPTON. 1955. Aspermatogenesis, anaphylaxis, and cutaneous sensitization induced in the guinea pig by homologous testicular extract. J. Exptl. Med. 101: 591–604. 44 FRECK, E. 1950. Nephritis durch Nierenautoantikörper. Z. Immunitätsforsch. 107: 411–417. 45 FRECK, E. 1950. Untersuchung zur Erzeugungvon Antikörpergegen homologes Lungengewebe. Z. Immunitätsforsch. 108: 253–258. 46 ROSE, N. R. & E. WITEBSKY. 1956. Studies on organ specificity. V. Changes in the thyroid glands of rabbits following active immunization with rabbit thyroid extracts. J. Immunol. 76: 416–427. 47 WITEBSKY, E., N. R. ROSE & S. SHULMAN. 1956. Studies of normal and malignant tissue antigens. 16 : 831–841. 48 WAKSMAN, B. H. & L. R. MORRISON. 1951. Tuberculin type sensitivity to spinal cord antigen in rabbits with isoallergic encephalomyelitis. J. Immunol. 66: 421–444. 49 MITCHISON, N. A. 1955. Studies on the immunological response to foreign tumor transplants in the mouse. J. Exptl. Med. 102: 157–177. 50 ELLIS, J. T. & J. G. KIDD. 1952. Inhibition of Brown-Pearce carcinoma by suspensions of lymph nodes and spleen from immune hosts. Cancer Research. 12: 259. 51 BILLINGHAM, R. E., L. BRENT & P. B. MEDAWAR. 1954. Quantitative studies on tissue transplantation immunity. II. The origin, strength and duration of actively and adoptively acquired immunity. Proc. Roy. Soc. 143B: 58–80. 52 GORER, P. A. 1956. The value of ascites tumors in problems of tumor immunity. Ann. N. Y. Acad. Sci. 63(5): 882–894. 53 WEAVER, J. M., G. H. ALGIRE & R. T. PREHN. 1955. The growth of cells in vivo in diffusion chambers. II. The role of cells in the destruction of homografts in mice. J. Natl. Cancer Inst. 15: 1737–1757. 54 MASUGI, M. 1933. Über das Wesen der spezifischen Veränderungen der Niere und der Leber durch das Nephrotoxin bzw. das Hepatotoxin. Beitr. pathol. Anat. u. allgem. Pathol. 91: 82–112. 55 SMADEL, J. E. 1936. Experimental nephritis in rats induced by injection of anti-kidney serum. I. Preparation and immunological studies of nephrotoxin. J. Exptl. Med. 64: 921–942. 56 HEYMANN, W. & H. Z. LUND. 1951. Nephrotic syndrome in rats. Pediatrics. 7: 691–706. 57 ACKROYD, J. F. 1955. Platelet agglutinins and lysins in the pathogenesis of thrombocytopenic purpura with a note on platelet groups. Brit. Med. Bull. 11: 28–35. 58 DAMESHEK, W. 1955. Hemolytic anemia, direct and indirect indications, pathogenetic mechanisms and classifications. Am. J. Med. 18: 315–325. 59 PRESSMAN, D. 1949. The zone of localization of antibodies. III. The specific localization of antibodies to rat kidney. Cancer. 2: 697–700. 60 WEINREB, M. S., K. H. SOULES & R. W. WISSLER. 1954. Quantitative studies of acute nephrotoxic nephritis in rats. Am. J. Pathol. 30: 311–335. 61 KAY, C. F. 1942. The mechanism of a form of glomerulonephritis: nephrotoxic nephritis in rabbits. Am. J. Med. Sci. 204: 483–490. 62 KNOWLTON, A. I., E. M. LOEB, H. C. STOERK & B. C. SEEGAL. 1947. Desoxycorticosterone acetate. The potentiation of its activity by sodium chloride. J. Exptl. Med. 85: 187–197. 63 LUMSDEN, T. 1937. On cytotoxins lethal to nucleated mammalian cells normal and malignant. Am. J. Cancer. 31: 430–440. 64 LUMSDEN, T. 1931. Tumour immunity: the effects of the eu- and pseudo-globulin fractions of anti-cancer sera on tissue cultures. J. Pathol. Bacteriol. 34: 349–355. 65 KALFAYAN, B. & J. G. KIDD. 1953. Structural changes produced in Brown-Pearce carcinoma cells by means of a specific antibody and complement. J. Expti. Med. 97: 145–162. 66 IMAGAWA, D. T., J. T. SYVERTON & J. J. BITTNER. 1954. The cytotoxicity of serum for mouse mammary cancer cells. II. The effects upon cells in culture. Cancer Research. 14: 8–11. 67 IMAGAWA, D. T., J. T. SYVERTON & J. J. BITTNER. 1954. The cytoloxicity of serum for mouse mammary cancer cells. I. The effects of admixture in vitro upon homoio-transplantability. Cancer Research. 14: 1–7. 68 MILLER, D. G. & T. C. Hsu. 1956. The action of cytotoxic antisera on the HeLa strain of human carcinoma. Cancer Research. 16: 306–312. 69 SCHREK, R. & F. W. PRESTON. 1956. Toxicily of homologous immune serum to a transplantable tumor: studies using phase microscopy and cinemicrography. J. Natl. Cancer Inst. 16: 1021–1045. 70 AIZAWA, M., T. IMAMURA, T. MOTOYAMA, S. KASAI, T. TOZAWA, H. ABE, S. SASAGE & K. IKEDA. 1952. On immunological therapy of Yoshida sarcoma. Gann. 42: 138–140. 71 MOTOYAMA, T., T. TOZAWA, M. AIZAWA & T. IMAMURA. 1952. The therapeutic effect upon Yoshida sarcoma of immune sera against Yoshida sarcoma of rabbit ab sorbed with several methods. Gann. 43: 248–250. 72 HORN, E. C. 1956. Ascites tumor development. II. Cytotoxicity of various antisera prepared against Ehrlich ascites tumor cell components. Cancer Research. 16: 595–599. 73 PRESSMAN, D. & L. KORNGOLD. 1954. The in vivo localization of anti-Wagner-osteogenic-sarcoma antibodies. Cancer. 6: 619–623. 74 KORNGOLD, L. & D. PRESSMAN. 1954. The localization of antilymphosarcoma antibodies in the Murphy lymphosarcoma of the rat. Cancer Research. 14: 96–102. 75 BALE, W. F., I. L. SPAR, R. L. GOODLAND & D. E. WOLFE. 1955. In vivo and in vitro studies of labeled antibodies against rat kidney and Walker carcinoma. Proc. Soc. Exptl. Biol. Med. 89: 564–568. 76 WISSLER, R. W., P. A. BARKER, M. H. FLAX, M. F. LAVIA & D. W. TALMAGE. 1956. A study of the preparation, localization and effects of antitumor antibodies labeled with I131. Cancer Research. 16: 761–773. 77 PRESSMAN, D., R. F. HILL & F. W. FOOTE, JR. 1949. Zone of localization of antimouse-kidney serum as determined by radioautographs. Science. 109: 65–66. 78 PRESSMAN, D. & H. N. EISEN. 1950. The zone of localization of antibodies. V. An attempt to saturate antibody-binding sites in the mouse kidney. J. Immunol. 64: 273–279. 79 TALMAGE, D. W., H. R. BAKER & W. AKESON. 1954. The separation and analysis of labeled antibodies. J. Infectious Diseases. 94: 199–212. 80 FLAX, M. H. 1956. The action of anti-Ehrlich ascites tumor antibody. Cancer Research. 16: 774–783. 81 BROWN, G. C. 1943. The complementary activity of mouse serum. J. Immunol. 46: 319–323. 82 McGHEE, R. B. 1952. Presence of complement in the serum of the mouse. Proc. Soc. Exptl. Biol. Med. 80: 419–420. 83 YOSHIDA, T. H. 1952. Cytological studies on cancer. V. Heteroplastic transplantation of the Yoshida sarcoma, with special regard to the behaviour of tumor cells. Gann. 43: 35–13. 84 HAUSCHKA, T. S., B. J. KVEDAR S. T. GRINNELL & D. B. AMOS. 1956. Immunoselection of polyploids from predominantly diploid cell populations. Ann. N. Y. Acad. Sci. 63(5): 683–705. 85 BLACK, M. M. & F. D. SPEER. 1953. Effects of cancer chemotherapeutic agents on dehydrogenase activity of human cancer tissue in vitro. Am. J. Clin. Pathol. 23: 218–227. 86 MICHAELIS, L. 1947. The nature of the interaction of nucleic acids and nuclei with basic dyestuffs. Cold Spring Harbor Symp. Quant. Biol. 12: 131–142. 87 DAY, E. D., J. PLANINSEK, L. KORNGOLD & D. PRESSMAN. 1956. Tumor-localizing antibodies purified from antisera against Murphy rat lymphosarcoma. J. Natl. Cancer Inst. 17: 517–532. 88 MURPHY, J. B. 1926. The lymphocyte in resistance to tissue grafting, malignant disease and tuberculous infection. Monogr. Rockefeller Inst. Med. Research. No. 21: 1–126. Citing Literature Volume69, Issue4Immunology and CancerDecember 1957Pages 773-794 ReferencesRelatedInformation