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The Arndt–Eistert Reaction in Peptide Chemistry: A Facile Access to Homopeptides

1995; Wiley; Volume: 34; Issue: 4 Linguagem: Inglês

10.1002/anie.199504711

1521-3773

Joachim Podlech, Dieter Seebàch,

Peptidase Inhibition and Analysis

By combination of an Arndt-Eistert reaction sequence and a peptide coupling, amino acids and peptides can be coupled with a second amino acid or a second peptide to give homopeptides, for example of type 1. This method has been employed to synthesize up to homohexapeptides.