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OCCURRENCE OF PHYSALAEMIN IN EXTRACTS OF THE SKIN OF PHYSALAEMUS FUSCUMACULATUS AND ITS PHARMACOLOGICAL ACTIONS ON EXTRAVASCULAR SMOOTH MUSCLE

1965; Wiley; Volume: 25; Issue: 2 Linguagem: Inglês

10.1111/j.1476-5381.1965.tb02056.x

2056-8177

G. Bertaccini, José Miguel Alfredo María Cei, V. Erspamer,

Pharmacological Effects of Natural Compounds

British Journal of Pharmacology and ChemotherapyVolume 25, Issue 2 p. 363-379 Free Access OCCURRENCE OF PHYSALAEMIN IN EXTRACTS OF THE SKIN OF PHYSALAEMUS FUSCUMACULATUS AND ITS PHARMACOLOGICAL ACTIONS ON EXTRAVASCULAR SMOOTH MUSCLE G. BERTACCINI, G. BERTACCINI Institute of Pharmacology, University of Parma, Parma, Italy, and the Institute of Biology, National University of Cuyo, Mendoza, ArgentinaSearch for more papers by this authorJ. M. CEI, J. M. CEI Institute of Pharmacology, University of Parma, Parma, Italy, and the Institute of Biology, National University of Cuyo, Mendoza, ArgentinaSearch for more papers by this authorV. ERSPAMER, V. ERSPAMER Institute of Pharmacology, University of Parma, Parma, Italy, and the Institute of Biology, National University of Cuyo, Mendoza, ArgentinaSearch for more papers by this author G. BERTACCINI, G. BERTACCINI Institute of Pharmacology, University of Parma, Parma, Italy, and the Institute of Biology, National University of Cuyo, Mendoza, ArgentinaSearch for more papers by this authorJ. M. CEI, J. M. CEI Institute of Pharmacology, University of Parma, Parma, Italy, and the Institute of Biology, National University of Cuyo, Mendoza, ArgentinaSearch for more papers by this authorV. ERSPAMER, V. ERSPAMER Institute of Pharmacology, University of Parma, Parma, Italy, and the Institute of Biology, National University of Cuyo, Mendoza, ArgentinaSearch for more papers by this author First published: October 1965 https://doi.org/10.1111/j.1476-5381.1965.tb02056.xCitations: 17AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat REFERENCES Anastasi, A. & Erspamer, V. (1963). The isolation and amino acid sequence of eledoisin, the active endecapeptide of the posterior salivary glands of Eledone. Arch. Biochem., 101, 56–65. 10.1016/0003-9861(63)90533-2 CASPubMedWeb of Science®Google Scholar Anastasi, A., Erspamer, V. & Bertaccini, G. (1965). Occurrence of bradykinin in the skin of Rana temporaria. Comp. Biochem. Physiol., 14, 43–52. 10.1016/0010-406X(65)90007-1 CASPubMedWeb of Science®Google Scholar Anastasi, A., Erspamer, V. & Cei, J. M. (1964). Isolation and amino acid sequence of physalaemin, the main active polypeptide of the skin of Physalaemus fuscumaculatus. Arch. Biochem., 108, 341–348. 10.1016/0003-9861(64)90395-9 CASPubMedWeb of Science®Google Scholar Bernardi, L., Bosisio, G., Goffredo, O. & De Castiglione, R. (1964). Synthesis of physalaemin. Experientia (Basel), 20, 490–491. 10.1007/BF02154065 CASPubMedWeb of Science®Google Scholar Bertaccini, G. & De Caro, G. (1965). The effect of physalaemin and related peptides on salivary secretion. J. Physiol. (Lond.), in the press. 10.1113/jphysiol.1965.sp007746 PubMedGoogle Scholar Cleugh, J. & Gaddum, J. H. (1963). The stability of purified preparations of substance P. Experientia (Basel), 19, 72–73. 10.1007/BF02148023 CASPubMedWeb of Science®Google Scholar De Caro, G. (1963). Azione dell'eledoisina sulla permeabilità capillare nell'uomo, nella cavia e nel ratto. Arch. int. Pharmacodyn., 146, 27–39. Google Scholar Erspamer, V., Anastasi, A., Bertaccini, G. & Cei, J. M. (1964). Structure and pharmacological actions of physalaemin, the main active polypeptide of the skin of Physalaemus fuscumaculatus. Experientia (Basel), 20, 489–490. 10.1007/BF02154064 CASPubMedWeb of Science®Google Scholar Erspamer, V., Bertaccini, G. & Cei, J. M. (1962). Occurrence of an eledoisin-like polypeptide (physalaemin) in skin extracts of Physalaemus fuscumaculatus. Experientia (Basel), 18, 562–563. 10.1007/BF02172180 CASPubMedGoogle Scholar Erspamer, V. & Falconieri Erspamer, G. (1962). Pharmacological actions of eledoisin on extravascular smooth muscle. Brit. J. Pharmacol., 19, 337–354. 10.1111/j.1476-5381.1962.tb01198.x CASPubMedWeb of Science®Google Scholar Haefeli, W. & Hürlimann, A. (1962). Substance P, a highly active naturally occurring polypeptide. Experientia (Basel), 18, 297–303. 10.1007/BF02151841 PubMedWeb of Science®Google Scholar Sherrington, C. S. (1919). Mammalian Physiology, pp. 76–79. Oxford: Clarendon Press. Google Scholar Citing Literature Volume25, Issue2October 1965Pages 363-379 ReferencesRelatedInformation