Antioxidant Activity and Alpha-Glucosidase Inhibitory Activity of Stings of Gleditsia sinensis Extracts
2011; Volume: 21; Issue: 1 Linguagem: Inglês
10.5352/jls.2011.21.1.62
ISSN2287-3406
AutoresJeung-Min Lee, Jae-Hee Park, Won-Mi Chu, Yi-Mook Yoon, Eunju Park, Hae-Ryong Park,
Tópico(s)Natural product bioactivities and synthesis
ResumoThis study was performed to investigate the physiological activities of stings of Gleditsia sinensis extracts. Antioxidant activity was evaluated by measuring total phenolic contents (TPC), comet assay, and 2.2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity (RSA). Anti-diabetic activity was measured by inhibition activities on α-glucosidase. Stings of Gleditsia sinensis extracts were prepared by extracting them with methanol and ethanol. The methanolic extracts showed the highest phenol content (1.12 g/100 g gallic acid equivalents). The α-glucosidase inhibitory activity of methanol extracts were 17.9% higher, and that of ethanol extracts were 10.3% higher at a concentration of 1 ㎎/ml. These results indicate that stings of Gleditsia sinensis might be potential candidates as antioxidant and anti-diabetic agents.
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