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It's time for “keratinocyte carcinoma” to replace the term “nonmelanoma skin cancer”

2014; Elsevier BV; Volume: 72; Issue: 1 Linguagem: Inglês

10.1016/j.jaad.2014.09.036

1097-6787

Chanté Karimkhani, Lindsay N. Boyers, Robert P. Dellavalle, Martin A. Weinstock,

Cutaneous lymphoproliferative disorders research

Basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) of the skin are the most common cancers in the United States and in predominantly light-skinned populations worldwide, and incidence is increasing. 1 Madan V. Lear J.T. Szeimies R.M. Non-melanoma skin cancer. Lancet. 2010; 375: 673-685 Abstract Full Text Full Text PDF PubMed Scopus (587) Google Scholar , 2 Albert M.R. Weinstock M.A. Keratinocyte carcinoma. CA Cancer J Clin. 2003; 53: 292-302 Crossref PubMed Scopus (73) Google Scholar , 3 Rodgers H.W. Weinstock M.A. Harris A.R. Hinckley M.R. Feldman S.R. Fleischer A.B. Coldiron B.M. Incidence estimate of nonmelanoma skin cancer in the United States, 2006. JAMA Dermatol. 2010; 146: 283-287 Google Scholar In the United States, they are more common than all other cancers combined, affecting millions of Americans each year. 1 Madan V. Lear J.T. Szeimies R.M. Non-melanoma skin cancer. Lancet. 2010; 375: 673-685 Abstract Full Text Full Text PDF PubMed Scopus (587) Google Scholar , 2 Albert M.R. Weinstock M.A. Keratinocyte carcinoma. CA Cancer J Clin. 2003; 53: 292-302 Crossref PubMed Scopus (73) Google Scholar Although they have a high cure rate, they are still responsible for well over 1000 deaths annually. 2 Albert M.R. Weinstock M.A. Keratinocyte carcinoma. CA Cancer J Clin. 2003; 53: 292-302 Crossref PubMed Scopus (73) Google Scholar , 4 Institute for Health Metrics and Evaluation. GBD compare. Available from: URL:http://vizhub.healthdata.org/gbd-compare/. Accessed June 25, 2014. Google Scholar In 2010 they were responsible for more disability-adjusted life years than melanoma in the United States. 4 Institute for Health Metrics and Evaluation. GBD compare. Available from: URL:http://vizhub.healthdata.org/gbd-compare/. Accessed June 25, 2014. Google Scholar They are also responsible for billions of dollars of health care expenditures, accounting for an estimated 4% of expenditures for cancer among adults. 5 Machlin S, Carper K, Kashihara D. Health care expenditures for non-melanoma skin cancer among adults, 2005-2008 (average annual). Statistical brief 345. November 2011. Agency for Healthcare Research and Quality; Rockville (MD). Available from: URL:http://www.meps.ahrq.gov/mepsweb/data_files/publications/st345/stat345.shtml. Accessed June 25, 2014. Google Scholar They are a leading contributor to the overall cost of skin disease. 5 Machlin S, Carper K, Kashihara D. Health care expenditures for non-melanoma skin cancer among adults, 2005-2008 (average annual). Statistical brief 345. November 2011. Agency for Healthcare Research and Quality; Rockville (MD). Available from: URL:http://www.meps.ahrq.gov/mepsweb/data_files/publications/st345/stat345.shtml. Accessed June 25, 2014. Google Scholar