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A compiled and systematic reference map of nucleosome positions across the Saccharomyces cerevisiae genome

2009; BioMed Central; Volume: 10; Issue: 10 Linguagem: Inglês

10.1186/gb-2009-10-10-r109

1474-760X

Cizhong Jiang, B. Franklin Pugh,

Genomics and Phylogenetic Studies

Abstract Nucleosomes have position-specific functions in controlling gene expression. A complete systematic genome-wide reference map of absolute and relative nucleosome positions is needed to minimize potential confusion when referring to the function of individual nucleosomes (or nucleosome-free regions) across datasets. We compiled six high-resolution genome-wide maps of Saccharomyces cerevisiae nucleosome positions from multiple labs and detection platforms, and report new insights. Data downloads, reference position assignment software, queries, and a visualization browser are available online http://atlas.bx.psu.edu/ .