Rectification in the smooth muscle cell membrane of rabbit aorta.
1976; Wiley; Volume: 258; Issue: 2 Linguagem: Inglês
10.1113/jphysiol.1976.sp011419
ISSN1469-7793
Autores Tópico(s)Photoreceptor and optogenetics research
Resumo1. The current‐voltage relation of the smooth muscle cell membrane of rabbit aorta was determined by the partition method. 2. No anomalous rectification was observed in any of the following solutions: normal Krebs, Na free choline, Na sulphate, and high K‐Na free sulphate. 3. Delayed rectification was seen on application of depolarizing current in both normal Krebs solution and Na free choline solution. 4. High concentration of K made the steady‐state current‐voltage relation almost linear in a voltage range of about 0 to ‐20mV. This effect, and steady‐state cathodal rectification which was seen in physiological solution, could be explained qualitatively by constant field theory without involving channels capable of anomalous rectification. 5. A slow decrease in K conductance, during application of large and long‐lasting hyperpolarizing currents, which occurs in skeletal muscle and is attributed to the tubule system, was never observed in the arteries either in Krebs, Na‐free choline, or Na sulphate solution.
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