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Effects of a Saturated Fat and High Cholesterol Diet on Memory and Hippocampal Morphology in the Middle-Aged Rat

2008; IOS Press; Volume: 14; Issue: 2 Linguagem: Inglês

10.3233/jad-2008-14202

1875-8908

Ann‐Charlotte Granholm, Heather A. Bimonte‐Nelson, Alfred Moore, Matthew Nelson, Linnea R. Freeman, Kumar Sambamurti,

Protein Hydrolysis and Bioactive Peptides

Diets rich in cholesterol and/or saturated fats have been shown to be detrimental to cognitive performance. Therefore, we fed a cholesterol (2%) and saturated fat (hydrogenated coconut oil, Sat Fat 10%) diet to 16-month old rats for 8 weeks to explor