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Patient and Tumor Characteristics and BRAF and KRAS Mutations in Colon Cancer, NCCTG/Alliance N0147

2014; Oxford University Press; Volume: 106; Issue: 7 Linguagem: Inglês

10.1093/jnci/dju106

1460-2105

Wilson I. Gonsalves, Michelle R. Mahoney, Daniel J. Sargent, Garth D. Nelson, Steven R. Alberts, Frank A. Sinicrope, Richard M. Goldberg, Paul J. Limburg, Stephen N. Thibodeau, Axel Grothey, Joleen M. Hubbard, Emily Chan, Suresh Nair, Jeffrey L. Berenberg, Robert R. McWilliams,

Colorectal Cancer Screening and Detection

BackgroundKRAS and BRAFV600E mutations are important predictive and prognostic markers, respectively, in colon cancer, but little is known about patient and clinical factors associated with them.