Expanding GSK's solvent selection guide – embedding sustainability into solvent selection starting at medicinal chemistry
2011; Royal Society of Chemistry; Volume: 13; Issue: 4 Linguagem: Inglês
10.1039/c0gc00918k
ISSN1463-9270
AutoresRichard K. Henderson, Concepción Jiménez‐González, David J. C. Constable, Sarah R. Alston, Graham G. A. Inglis, Gail Fisher, James Sherwood, Steve P. Binks, Alan D. Curzons,
Tópico(s)Various Chemistry Research Topics
ResumoSolvents make a large contribution to the environmental impact of manufacturing processes of active pharmaceutical ingredients (API), as well as playing an important role in other chemical industries, with millions of tons used and disposed of each year. GlaxoSmithKline (GSK) has previously reported on the both the development of a GSK solvent selection guide and the incorporation of solvent life cycle inventory and assessment information. The GSK solvent selection guide has been further enhanced by:
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