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Loss of Vancomycin-Resistant Enterococcus Fecal Dominance in an Organ Transplant Patient With Clostridium difficile Colitis After Fecal Microbiota Transplant

2015; Oxford University Press; Volume: 2; Issue: 2 Linguagem: Inglês

10.1093/ofid/ofv078

2328-8957

Joshua Stripling, Ranjit Kumar, John W. Baddley, Anoma Nellore, Paula Dixon, Donna Howard, Travis Ptacek, Elliot J. Lefkowitz, José Tallaj, William H. Benjamin, Casey D. Morrow, J. Martín Rodríguez,

Microscopic Colitis

We report the use of fecal microbiota transplantation in a single heart-kidney transplant recipient with recurrent Clostridium difficile, vancomycin-resistant Enterococcus (VRE) fecal dominance, and recurrent VRE infections. Fecal microbiota transplantation resulted in the reconstruction of a diverse microbiota with (1) reduced relative abundance of C difficile and VRE and (2) positive clinical outcome.