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The Use of Non-Uniform Deuterium Labelling ['NMR-Window'] To Study the NMR Structure of a 21mer RNA Hairpin

1996; Oxford University Press; Volume: 24; Issue: 7 Linguagem: Inglês

10.1093/nar/24.7.1187

1362-4962

András Földesi, Shun-ichi Yamakage, Frida Nilsson, T. V. Maltseva, Jyoti Chattopadhyaya,

Protein Structure and Dynamics

The first synthesis of a non-uniformly deuterium labelled 21mer RNA is reported using our 'NMR-window' concept, showing its unique application in the unambiguous NMR assignment of the non-exchangeable aromatic and sugar protons.