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A Systems Approach to Analysis of Molecular Complexity in Breast Cancer

2009; American Association for Cancer Research; Volume: 15; Issue: 2 Linguagem: Inglês

10.1158/1078-0432.ccr-08-2620

1557-3265

Bryan T. Hennessy, Ana M. González-Angulo, Mark Carey, Gordon B. Mills,

Cancer Cells and Metastasis

Abstract In this issue of Clinical Cancer Research, Andre et al. apply high-resolution arrays to elucidate copy number anomalies in breast cancer. They identify distinct copy number anomaly patterns in different breast cancer subtypes that implicate a number of genes as potential therapeutic targets and as potential markers of therapy responsiveness.