Comparison of a Commercial Multiplex Real-Time PCR to the Cell Cytotoxicity Neutralization Assay for Diagnosis of Clostridium difficile Infections
2009; American Society for Microbiology; Volume: 47; Issue: 11 Linguagem: Inglês
10.1128/jcm.01280-09
ISSN1098-660X
AutoresHaihui Huang, Andrej Weintraub, Hong Fang, Carl Erik Nord,
Tópico(s)Microscopic Colitis
ResumoA commercial multiplex real-time PCR assay (Cepheid Xpert C. difficile assay) for the diagnosis of Clostridium difficile infection was evaluated. The sensitivity and specificity of the Cepheid assay were 97.1% and 93.0% for fresh stools, using the cell cytotoxicity neutralization assay as the reference. Using PCR ribotyping as the reference for ribotype 027 strains, the corresponding figures were 100% and 98.1%, respectively.
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