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A comparison of sample size methods for the logrank statistic

1992; Wiley; Volume: 11; Issue: 2 Linguagem: Inglês

10.1002/sim.4780110205

1097-0258

Edward Lakatos, K. K. Gordon Lan,

Advanced Statistical Process Monitoring

Abstract Several methods are available for sample size calculation for clinical trials when survival curves are to be compared using the logrank statistic. We discuss advantages and disadvantages of some of these methods, and present simulation results under exponential, proportional hazards and non‐proportional hazard situations.