Activation of the NOTCH1 pathway in chronic lymphocytic leukemia
2012; Ferrata Storti Foundation; Volume: 97; Issue: 3 Linguagem: Inglês
10.3324/haematol.2012.061721
ISSN1592-8721
Autores Tópico(s)Cancer-related Molecular Pathways
ResumoChronic lymphocytic leukemia (CLL) is the most common leukemia in adults and is characterized by the monoclonal expansion of CD5+ B cells. CLL shows clinical heterogeneity, from patients with very stable disease to patients with a rapidly progressive disease that is refractory to therapy. In
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