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Comparison of 99mTc-DTPA renal dynamic imaging with modified MDRD equation for glomerular filtration rate estimation in Chinese patients in different stages of chronic kidney disease

2006; Oxford University Press; Volume: 22; Issue: 2 Linguagem: Inglês

10.1093/ndt/gfl603

1460-2385

Yingchun Ma, Luo Zuo, C.-L. Zhang, Mingyue Wang, R.-F. Wang, H.-Y. Wang,

Cardiovascular Function and Risk Factors

Background. The renal dynamic imaging method (modified Gate's method) with 99mTc-diethylene triamine pentaacetic acid (99mTc-DTPA) is simple and less time consuming for glomerular filtration rate (GFR) estimation than other methods. However, its diagnostic performance as a surrogate marker of GFR is questioned increasingly. Recently, the modified Modification of Diet in Renal Disease (MDRD) study equation based on data from Chinese patients of chronic kidney disease (CKD) showed significant performance improvement. In the present study, the renal dynamic imaging methods and the modified abbreviated MDRD equation were compared with the plasma clearance method.