Portal de Periódicos da CAPES

Successful thalamic deep brain stimulation for orthostatic tremor

2008; Wiley; Volume: 23; Issue: 13 Linguagem: Inglês

10.1002/mds.22001

1531-8257

Jorge Guridi, María Rodríguez‐Oroz, Javier Arbizu, Manuel Alegre, Elena Prieto, Ignacio Landecho, Miguel Manrique, Julio Artieda, José Á. Obeso,

Glycogen Storage Diseases and Myoclonus

We report a patient with severe orthostatic tremor (OT) unresponsive to pharmacological treatments that was successfully controlled with thalamic (Vim, ventralis intermedius nucleus) deep brain stimulation (DBS) over a 4-year period. Cortical activity associated with the OT revealed by EEG back-averaging and fluoro-deoxi-glucose PET were also suppressed in parallel with tremor arrest. This case suggests that Vim-DBS may be a useful therapeutic approach for patients highly disabled by OT.