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Factors affecting pregnancy outcome of intrauterine insemination cycles in couples with favourable female characteristics

2011; Informa; Volume: 31; Issue: 5 Linguagem: Inglês

10.3109/01443615.2011.569780

1364-6893

B. Demir, Berna Dilbaz, Özgür Çınar, Burak Karadağ, Yasemin Taşçı, Mehmet Koçak, Serdar Dilbaz, Ümit Göktolga,

Reproductive Health and Technologies

The aim of the presented study is to determine the effect of different sperm parameters on the pregnancy rate of intrauterine insemination (IUI) cycles in women with favourable fertility characteristics treated for infertility. Medical records of 212 infertile couples who had undergone a total of 253 cycles were reviewed retrospectively. Inclusion criteria for women were age 5, FSH <15 IU/ml, and at least one patent tube documented by HSG or laparoscopy. Clinical pregnancy rates were achieved as 15.8% per cycle, and 18.8% per couple. Woman's age, partner's age, total number of motile sperm (TMS) and motility, significantly influenced pregnancy rate. Pregnancy rate was the highest when women were aged 10 × 10(6). Partner's age significantly affected the pregnancy rate per cycle in women aged 10 × 10(6). Woman's age (OR: 5.4 95% CI: 1.2-24.3) and TMS (OR: 0.06 95% CI: 0.003-0.89) were predictor variables as regards to pregnancy. Pregnancy rate was the highest in IUI cycles when woman was 10 × 10(6), and morphology was >4%. Male age was found to be another determining factor for IUI success, even if they had a normal spermiogram.