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Comparison of the 308‐nm excimer laser with the 308‐nm excimer lamp in the treatment of vitiligo – a randomized bilateral comparison study

2013; Wiley; Volume: 29; Issue: 1 Linguagem: Inglês

10.1111/phpp.12015

1600-0781

Qiong Shi, Kai Li, Jun Fu, Yanchun Wang, Cuiling Ma, Qiang Li, Chunying Li, Tianwen Gao,

Skin Protection and Aging

Abstract Background Vitiligo is an acquired pigment disorder characterized by areas of depigmented skin resulting from the loss of epidermal melanocytes. Recently, several investigations have documented the benefits of excimer phototherapy (e.g., using the 308‐nm excimer laser or the 308‐nm excimer lamp) for the treatment of vitiligo. Aim To compare the effectiveness of the 308‐nm excimer laser with the 308‐nm excimer lamp in the treatment of vitiligo patients. Methods This intervention study was designed as a randomized self‐control trial. Fourteen subjects with 48 symmetrical vitiligo lesions were enrolled in this study. One lesion was treated with the 308‐nm excimer laser, and its counterpart was treated with the 308‐nm excimer lamp. Lesions were treated three times a week with the same dose on both sides for a total of 20 sessions. Results All of the patients completed the study, and 48 lesions were treated. The two treatments exhibited similar results in terms of repigmentation. Conclusions The 308‐nm excimer lamp and the 308‐nm excimer laser exhibited similar efficacies in treating vitiligo.