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The SCID-hu Mouse: A Small Animal Model for HIV Infection and Pathogenesis

1991; Annual Reviews; Volume: 9; Issue: 1 Linguagem: Inglês

10.1146/annurev.iy.09.040191.002151

1545-3278

Joseph M. McCune, Hideto Kaneshima, John F. Krowka, Reiko Namikawa, Henry C. Outzen, Bruno Péault, Linda Rabin, C.-C. Shih, E J Yee, M Lieberman,

HIV Research and Treatment

Exhausted CD8 T (Tex) cells are a distinct cell lineage that arise during chronic infections and cancers in animal models and humans. Tex cells are characterized by progressive loss of effector functions, high and sustained inhibitory receptor expression, ...Read More