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Clindamycin Palmitate Flavored Granules. Multidose Tolerance, Absorption, and Urinary Excretion Study in Healthy Children

1972; Wiley; Volume: 12; Issue: 2-3 Linguagem: Inglês

10.1002/j.1552-4604.1972.tb00149.x

ISSN

2375-0928

Autores

Ray M. DeHaan, Diana Schellenberg,

Tópico(s)

Cancer therapeutics and mechanisms

Resumo

The Journal of Clinical Pharmacology and New DrugsVolume 12, Issue 2-3 p. 74-83 Clindamycin Palmitate Flavored Granules. Multidose Tolerance, Absorption, and Urinary Excretion Study in Healthy Children RAY M. DeHAAN M.D., M.S., F.A.C.P., Corresponding Author RAY M. DeHAAN M.D., M.S., F.A.C.P. Infectious Diseases Research Department, The Upjohn Company, Kalamazoo, Mich.The Upjohn Company, 301 Henrietta Street, Kalamazoo, Michigan 49001.Search for more papers by this authorDIANA SCHELLENBERG M.A., DIANA SCHELLENBERG M.A. Infectious Diseases Research Department, The Upjohn Company, Kalamazoo, Mich.Search for more papers by this author RAY M. DeHAAN M.D., M.S., F.A.C.P., Corresponding Author RAY M. DeHAAN M.D., M.S., F.A.C.P. Infectious Diseases Research Department, The Upjohn Company, Kalamazoo, Mich.The Upjohn Company, 301 Henrietta Street, Kalamazoo, Michigan 49001.Search for more papers by this authorDIANA SCHELLENBERG M.A., DIANA SCHELLENBERG M.A. Infectious Diseases Research Department, The Upjohn Company, Kalamazoo, Mich.Search for more papers by this author First published: February‐March 1972 https://doi.org/10.1002/j.1552-4604.1972.tb00149.xCitations: 4AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL References 1 DeHaan, R. M., Schellenberg, D., Vanden-Bosch, W. D., and Maile, M. L.: Clindamycin palmitate in healthy men: general tolerance and effect on stools. Submitted for publication. 2 Data on file with The Upjohn Company, Kalamazoo, Mich. 3 Geddes, A. M., Bridgwater, F. A. J., Williams, D. M., Oon, J., and Grimshaw, C. J.: Clinical and bacteriological studies with clindamycin. Brit. Med. J. 2: 703 (1970). 4 Oppenheimer, S., and Turck, M.: Laboratory and clinical evaluation of 7-chloro-7-deoxylincomycin. Amer. J. Med. Sci. 256: 314 (1969). 5 Kanee, B.: Clindamycin in the treatment of pyoderma. Appl. Therap. 11: 482 (1969). 6 Pelzl, H.: Clinical experience with a new lincomycin derivative in the therapy of surgical infections. Arzneimittelforsch. 19: 117 (1969). 7 Schlegel, D., and Hieber, E.: Practical experiences with 7-chloro-7-deoxy-lincomycin in jaw surgery. Zahnärztliche Praxis 20: 37 (1969). 8 Randolph, M. F., Redys, J. J., and Hibbard, E. W.: Streptococcal pharyngitis. 3. Streptococcal recurrence rates following therapy with penicillin or with clindamycin. Del. Med. J. 42: 87 (1970). 9 Magerlein, B. J., Birkenmeyer, R. D., and Kagan, F.: Chemical modification of lincomycin. Antimicrob. Agents Chemotherap: 727 (1966). 10 McGehee, R. F., Jr., Smith, C. B., Wilcox, G., and Finland, M.: Comparative studies of antibacterial activity in vitro and absorption and excretion of lincomycin and clinimycin. Amer. J. Med. Sci. 256: 279 (1968). 11 Meyers, B. R., Kaplan, K., and Weinstein, L.: Microbiological and pharmacological behavior of 7-chlorolincomycin. Appl. Microbiol. 17: 653 (1969). 12 Garrison, D. W., DeHaan, R. M., and Lawson, J. B.: Comparison of in vitro antibacterial activities of 7-chloro-7-deoxylincomycin, lincomycin and erythromycin. Antimicrob. Agents Chemotherap.: 397 (1967). 13 Phillips, I., Fernandes, R., and Warren, C.: In-vitro comparison of erythromycin, lincomycin, and clindamycin. Brit. Med. J. 2: 89 (1970). 14 Hatch, L. A.: An in vitro survey of sensitivity to clinimycin in a hospital laboratory. Can. J. Public Health 60: 41 (1969). 15 Sinkula, A. A., Morozowich, W., and Rower, E. L.: The chemical modification of clindamycin: synthesis and evaluation of selected esters. Abstracts of Papers, APhA Acad. Pharm. Sci., 117th Annual Meeting APhA, Washington, D.C., April 1970, p. 63. 16 Sun, F., and Brodasky, T.: Personal communication. Citing Literature Volume12, Issue2-3February‐March 1972Pages 74-83 ReferencesRelatedInformation

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