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The role of different K antigens of Escherichia coli in phagocytosis by polymorphonuclear leukocytes

1984; Microbiology Society; Volume: 17; Issue: 2 Linguagem: Inglês

10.1099/00222615-17-2-141

1473-5644

A. M. J. J. Verweij-Van Vught, F. Namavar, P. G. H. Peerbooms, M. Sparrius, D. M. MacLaren,

Bacterial Infections and Vaccines

The importance of K antigens from six strains of Escherichia coli for the interaction with polymorphonuclear leukocytes (PMNL) was studied. The major factor influencing this interaction was the ability of strains to activate complement by the classical route during opsonisation, this process being reduced for most K-positive strains. Interference of K antigens with the functioning of common pili as adhesions of eukaryotic cells was not observed nor a toxic effect of K antigens on PMNL.