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In Vitro Fermentation of Breast Milk Oligosaccharides by Bifidobacterium infantis and Lactobacillus gasseri

2006; American Society for Microbiology; Volume: 72; Issue: 6 Linguagem: Inglês

10.1128/aem.02515-05

1098-5336

Robert E. Ward, Milady R. Niñonuevo, David A. Mills, Carlito B. Lebrilla, J. Bruce German,

Microbial Metabolites in Food Biotechnology

ABSTRACT It has been proposed that human milk oligosaccharides (HMO) function as a prebiotic for bifidobacteria, yet this activity has not been adequately investigated. In this study, Bifidobacterium infantis was shown to ferment purified HMO as a sole carbon source, while another gut commensal, Lactobacillus gasseri , did not ferment HMO. Our results support the hypothesis that HMO selectively amplify bacterial populations in the infant intestine.