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A review: microRNA detection methods

2014; Royal Society of Chemistry; Volume: 13; Issue: 8 Linguagem: Inglês

10.1039/c4ob02104e

1477-0539

Tian Tian, Jiaqi Wang, Xiang Zhou,

RNA Interference and Gene Delivery

MicroRNA (miRNA) detection is of considerable significance in both disease diagnosis and in the study of miRNA function. The importance of miRNA itself is due to the complicated regulatory functions it plays in various life processes and its close relationship with some diseases. Traditional methods for miRNA detection do not meet the current demands, so various novel methods have been developed with a special focus on sensitivity and specificity. Herein, we summarize and discuss the newly developed miRNA detection methods.