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P3‐158: Performance of mild cognitive impairment and Alzheimer's disease patients in the Fuld Object‐Memory Evaluation (FOME)

2008; Wiley; Volume: 4; Issue: 4S_Part_17 Linguagem: Inglês

10.1016/j.jalz.2008.05.1724

1552-5279

Cláudia Maia Memória, Mônica Sanches Yassuda, Mariana K. Flaks, Luciane Viola, Fernanda Pereira, Orestes Vicente Forlenza,

Dementia and Cognitive Impairment Research

The FOME is a routinely used neuropsychological test which evaluates the different aspects of verbal memory (storage, retrieval and retention) and learning slope. Deficits in episodic memory are an early feature of Mild Cognitive Impairment (MCI) and Alzheimer's disease (AD). Objectives: we aimed to describe the performance of MCI and AD patients, compared to patients without evidence of cognitive disorders, in the FOME scores (storage, retrieval, repeated retrieval, ineffective reminders and delayed recall). The FOME was part of a comprehensive neuropsychological battery administered in patients enrolled in the Psychogeriatric Unit of the LIM-27, Institute of Psychiatry, University of São Paulo. Diagnoses of MCI and AD were reached at multidisciplinary consensus meetings. AD patients had significantly worse performance than MCI patients and controls in all FOME scores. On the other hand, MCI patients had significantly worse performance in the storage (p<.001), delayed recall (p=.002), and repeated retrieval (p<.001), compared to controls. The FOME can help to recognize patients with subtle memory deficits and may aid in the identification of individuals at higher risk of AD, i.e. patients with MCI.