Produção Nacional
Revisado por pares
Swine and Poultry Pathogens: the Complete Genome Sequences of Two Strains of Mycoplasma hyopneumoniae and a Strain of Mycoplasma synoviae
2005; American Society for Microbiology; Volume: 187; Issue: 16 Linguagem: Inglês
10.1128/jb.187.16.5568-5577.2005
ISSN1098-5530
AutoresAna Tereza Ribeiro de Vasconcelos, Henrique Bunselmeyer Ferreira, Cristiano Valim Bizarro, Sandro L. Bonatto, Marcos Oliveira de Carvalho, Paulo Marcos Pinto, Darcy F. de Almeida, Luiz Gonzaga Paula de Almeida, Rosana de Almeida, Leonardo Alves-Filho, Enedina Nogueira de Assunção, Vasco Azevedo, Maurı́cio Reis Bogo, Marcelo M. Brígido, Marcelo Brocchi, Hélio Almeida Burity, Anamaria A. Camargo, Sandro da Silva Camargo, Marta S. P. Carepo, Dirce Maria Carraro, Júlio Cézar de Mattos Cascardo, Luiza Amaral de Castro, Gisele Cavalcanti, Gustavo Chemale, Rosane G. Collevatti, Cristina W. Cunha, Bruno Dallagiovanna, Bibiana Paula Dambrós, Odir Antônio Dellagostin, Clarissa Falcão, Fabiana Fantinatti‐Garboggini, Maria Sueli Soares Felipe, L. Fiorentin, Glória Regina Franco, Nara Suzy Aguiar de Freitas, Diego Frı́as, Thalles B. Grangeiro, Edmundo C. Grisard, C. T. Guimarães, Mariangela Hungría, S. N. Jardim, Marco Aurélio Krieger, Jomar Pereira Laurino, Lucymara Fassarella Agnez‐Lima, Maryellen I. Lopes, Élgion L. S. Loreto, Humberto Maciel França Madeira, Gilson P. Manfio, Andréa Queiróz Maranhão, Christyanne T. Martinkovics, Sílvia Regina Batistuzzo de Medeiros, María Manuela Martins, Márcia Neiva, Cicero Eduardo Ramalho-Neto, Marisa Nicolás, Sérgio C. Oliveira, Maria Paula Paixão, Fábio O. Pedrosa, Sérgio D.J. Pena, Maristela Pereira, Lilian Pereira‐Ferrari, I. A. Piffer, Luciano da Silva Pinto, Deise Porto Potrich, Anna C. M. Salim, Fabrício R. Santos, Renata Schmitt, Maria Paula Cruz Schneider, Augusto Schrank, Irene Silveira Schrank, Adriana F. Schuck, Héctor N. Seuánez, Denise W. Silva, Rosane Silva, Sérgio C. Silva, Célia M.A. Soares, Kelly Rose Lobo de Souza, Rangel Celso Souza, Charley Christian Staats, Maria Berenice Reynaud Steffens, Santuza Maria Ribeiro Teixeira, Turán P. Ürményi, Marilene Henning Vainstein, Luciana W. Zuccherato, Andrew J.G. Simpson, Arnaldo Zaha,
Tópico(s)Plant Virus Research Studies
ResumoThis work reports the results of analyses of three complete mycoplasma genomes, a pathogenic (7448) and a nonpathogenic (J) strain of the swine pathogen Mycoplasma hyopneumoniae and a strain of the avian pathogen Mycoplasma synoviae; the genome sizes of the three strains were 920,079 bp, 897,405 bp, and 799,476 bp, respectively. These genomes were compared with other sequenced mycoplasma genomes reported in the literature to examine several aspects of mycoplasma evolution. Strain-specific regions, including integrative and conjugal elements, and genome rearrangements and alterations in adhesin sequences were observed in the M. hyopneumoniae strains, and all of these were potentially related to pathogenicity. Genomic comparisons revealed that reduction in genome size implied loss of redundant metabolic pathways, with maintenance of alternative routes in different species. Horizontal gene transfer was consistently observed between M. synoviae and Mycoplasma gallisepticum. Our analyses indicated a likely transfer event of hemagglutinin-coding DNA sequences from M. gallisepticum to M. synoviae.
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