Artigo Produção Nacional Revisado por pares

Acquired Factor VIII and von Willebrand Factor (aFVIII/VWF) Deficiency and Hypothyroidism in a Case With Hypopituitarism

2008; SAGE Publishing; Volume: 16; Issue: 1 Linguagem: Inglês

10.1177/1076029608319948

ISSN

1938-2723

Autores

Miriam C. Oliveira, Caroline K. Kramer, Caroline Possa Marroni, Carolina Garcia Soares Leães, Luciana Verçoza Viana, Sérgio Roithman, Alexandre Schmaedecke, Júlia Fernanda Semmelmann Pereira‐Lima,

Tópico(s)

Myeloproliferative Neoplasms: Diagnosis and Treatment

Resumo

This article reports a female who presented with bleeding, acquired factor VIII and von Willebrand factor (aFVIII-VWF) deficiency, and central deficiency in the thyroid and adrenal axis (Sheehan’s syndrome). After starting hormone replacement therapy, relief of bleeding manifestations was associated with correction of both FVIII and VWF to normal. This report draws attention to a rare association between the acquired form of von Willebrand disease and hypothyroidism of central origin.

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