The physical toxicity of chemicals. VI. Relationships between the boiling points of liquids and the toxicities of their vapours
1966; Wiley; Volume: 16; Issue: 3 Linguagem: Inglês
10.1002/jctb.5010160308
ISSN1934-998X
Autores Tópico(s)thermodynamics and calorimetric analyses
ResumoAbstract The following equation gives the relation between the toxic concentration C t of the vapour to the absolute boiling point T B of a physically toxic liquid: log 10 C t (at 25°) = log 10 C B ‐1.43 × 10 −4 T b 1.7 ‐ E A +0.09 Here, C B is a measure of the intensity of the toxicity and E A accounts for any difference between molecular interaction in the vapour and in the biophase involved in the toxicity. The equation is useful for the estimation of toxicities and for the classification of toxic substances. It is deduced that compounds with boiling points (° K ) above 509( E A ‐ log 10 C B +1.22) 0.588 will show no physical toxicity.
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