The Victor C++ library for protein representation and advanced manipulation
2014; Oxford University Press; Volume: 31; Issue: 7 Linguagem: Inglês
10.1093/bioinformatics/btu773
ISSN1367-4811
AutoresLayla Hirsh, Damiano Piovesan, Manuel Giollo, Carlo Ferrari, Silvio C. E. Tosatto,
Tópico(s)RNA and protein synthesis mechanisms
ResumoAbstract Motivation: Protein sequence and structure representation and manipulation require dedicated software libraries to support methods of increasing complexity. Here, we describe the VIrtual Constrution TOol for pRoteins (Victor) C++ library, an open source platform dedicated to enabling inexperienced users to develop advanced tools and gathering contributions from the community. The provided application examples cover statistical energy potentials, profile–profile sequence alignments and ab initio loop modeling. Victor was used over the last 15 years in several publications and optimized for efficiency. It is provided as a GitHub repository with source files and unit tests, plus extensive online documentation, including a Wiki with help files and tutorials, examples and Doxygen documentation. Availability and implementation: The C++ library and online documentation, distributed under a GPL license are available from URL: http://protein.bio.unipd.it/victor/. Contact: silvio.tosatto@unipd.it
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