Artigo Acesso aberto Produção Nacional Revisado por pares

Competing regression models for longitudinal data

2012; Wiley; Volume: 54; Issue: 2 Linguagem: Inglês

10.1002/bimj.201100056

ISSN

1521-4036

Autores

Airlane Pereira Alencar, Júlio M. Singer, Francisco Marcelo Monteiro da Rocha,

Tópico(s)

Bayesian Methods and Mixture Models

Resumo

The choice of an appropriate family of linear models for the analysis of longitudinal data is often a matter of concern for practitioners. To attenuate such difficulties, we discuss some issues that emerge when analyzing this type of data via a practical example involving pretest–posttest longitudinal data. In particular, we consider log‐normal linear mixed models (LNLMM), generalized linear mixed models (GLMM), and models based on generalized estimating equations (GEE). We show how some special features of the data, like a nonconstant coefficient of variation, may be handled in the three approaches and evaluate their performance with respect to the magnitude of standard errors of interpretable and comparable parameters. We also show how different diagnostic tools may be employed to identify outliers and comment on available software. We conclude by noting that the results are similar, but that GEE‐based models may be preferable when the goal is to compare the marginal expected responses.

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