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Hemolytic uremic syndrome following taipan envenomation with response to plasmapheresis

1997; Elsevier BV; Volume: 29; Issue: 4 Linguagem: Inglês

10.1080/00313029700169385

1465-3931

Ralph Cobcroft, A. Williams, David Cook, David J. Williams, Paul P. Masci,

Epilepsy research and treatment

We report a case of hemolytic uremic syndrome (HUS) in a 33 year old male who was bitten by a taipan, with apparent massive envenomation. The microangiopathic hemolytic anemia (MAHA) and thrombocytopenic aspects of his HUS appeared to respond to plasmapheresis, but his anuric renal failure persisted. He also had prolonged severe muscular paralysis which gradually began to resolve over the course of two weeks. At this point he suffered a cardiac arrest sustaining severe and subsequently fatal hypoxic brain injury. This case raises the possibility that the taipan venom may have induced HUS by damaging the renal endothelium. His cardiac arrest was not apparently related to his HUS.